Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19


Authors.Maximilian Ackermann, M.D., Stijn E. Verleden, Ph.D., Mark Kuehnel, Ph.D., Axel Haverich, M.D., Tobias Welte, M.D., Florian Laenger, M.D., Arno Vanstapel, Ph.D., Christopher Werlein, M.D., Helge Stark, Ph.D., Alexandar Tzankov, M.D., William W. Li, M.D., Vincent W. Li, M.D., et al. July…[...]

Endothelial thrombomodulin downregulation caused by hypoxia contributes to severe infiltration and coagulopathy in COVID-19 patient lungs


Authors: Taejoon Won, Megan K. Wood, David M. Hughes, Monica V. Talor, Zexu MaJowaly Schneider, et al. Published:January 12, 2022DOI:https://doi.org/10.1016/j.ebiom.2022.103812 Background Thromboembolism is a life-threatening manifestation of coronavirus disease 2019…[...]

Risk of severe COVID-19 disease with ACE inhibitors and angiotensin receptor blockers: cohort study including 8.3 million people


Julia Hippisley-Cox1, Duncan Young2,3, Carol Coupland4, Keith M Channon5, Pui San Tan6, David A Harrison7, Kathryn Rowan8,  Paul Aveyard6, Ian D Pavord9, Peter J Watkinson5,10Correspondence to Prof Julia Hippisley-Cox, Primary Care Health Sciences, University of Oxford, Oxford OX1  Abstract…[...]

How does coronavirus kill? Clinicians trace a ferocious rampage through the body, from brain to toes


Authors: By Meredith Wadman, Jennifer Couzin-Frankel, Jocelyn Kaiser, Catherine MatacicApr. 17, 2020 , 6:45 PM On rounds in a 20-bed intensive care unit one recent day, physician Joshua Denson assessed two patients with seizures,…[...]

Asthmatics at no higher risk getting or dying from COVID-19, assessment of studies consisting of 587,000 people shows


Authors: February 19, 2021Source:Taylor & Francis Group Summary: A review of 57 studies shows people with asthma had a 14 percent lower risk of getting COVID-19 and were significantly less…[...]

Histopathological observations in COVID-19: a systematic review


Authors: Vishwajit Deshmukh1, Rohini Motwani, Ashutosh Kumar3, Chiman Kumari4, Khursheed Raza5Correspondence to Dr Rohini Motwani, Department of Anatomy, ESIC Medical College and Hospital, Sanathnagar, Hyderabad, Telangana, India; rohinimotwani@gmail.com Abstract Background Coronavirus disease-2019 (COVID-19) has caused a…[...]

Pathological findings in organs and tissues of patients with COVID-19: A systematic review


Authors: Sasha Peiris, Hector Mesa, Agnes Aysola, Juan Manivel, Joao Toledo, Marcio Borges-Sa, Sylvain Aldighieri, Ludovic Reveiz Abstract Background Coronavirus disease (COVID-19) is the pandemic caused by SARS-CoV-2 that has…[...]

Late Complications of COVID-19; a Systematic Review of Current Evidence


Authors: SeyedAhmad SeyedAlinaghi,1Amir Masoud Afsahi,2Mehrzad MohsseniPour,1Farzane Behnezhad,3Mohammad Amin Salehi,1Alireza Barzegary,4Pegah Mirzapour,1Esmaeil Mehraeen,5,* and Omid Dadras6 Introduction Introduction: COVID-19 is a new rapidly spreading epidemic. The symptoms of this disease could be diverse…[...]

Severe covid-19 pneumonia: pathogenesis and clinical management


Authors: Amy H Attaway, assistant professor of medicine, associate director, COPD center1,  Rachel G Scheraga, assistant professor of medicine1 2,  Adarsh Bhimraj, head, section of neurological infections; staff, infectious diseases1,  Michelle…[...]