Category: Lung Disease

Posted on | Posted on John Murphy | Leave a Comment on Cardiorespiratory dysautonomia in post-COVID-19 condition: Manifestations, mechanisms and management

Cardiorespiratory dysautonomia in post-COVID-19 condition: Manifestations, mechanisms and management

Artur Fedorowski, Monika Fagevik Olsén, Frida Nikesjö, Christer Janson, Judith Bruchfeld, Maria Lerm, Kristofer Hedma: May 2023, Journal of Internal MedicineVolume 294, Issue 5 p. 548-562 Abstract A significant proportion of COVID-19 patients experience debilitating symptoms for…[...]

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Posted on | Posted on John Murphy | Leave a Comment on Dysautonomia and small fiber neuropathy in post-COVID condition and Chronic Fatigue Syndrome

Dysautonomia and small fiber neuropathy in post-COVID condition and Chronic Fatigue Syndrome

N. Azcue, R. Del Pino, et. al., Journal of Translational Medicine volume 21, Article number: 814 (2023)  Abstract Background Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and post-COVID condition can present similarities such as fatigue, brain fog, autonomic and…[...]

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Posted on | Posted on John Murphy | Leave a Comment on C5aR1 signaling triggers lung immunopathology in COVID-19 through neutrophil extracellular traps

C5aR1 signaling triggers lung immunopathology in COVID-19 through neutrophil extracellular traps

Bruna M. Silva,1,2 Giovanni F. Gomes,1 Flavio P. Veras,1 Seppe Cambier,3 Gabriel V.L. Silva,1,2 Andreza U. Quadros,1 Diego B. Caetité,1,2 Daniele C. Nascimento,1,2 Camilla M. Silva,1,2 Juliana C. Silva,1 Samara Damasceno,1 Ayda H. Schneider,1 Fabio Beretta,3 Sabrina S. Batah,4 Icaro M.S. Castro,5 Isadora M. Paiva,1 Tamara…[...]

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Posted on | Posted on John Murphy | Leave a Comment on Mast cell activation in lungs during SARS-CoV-2 infection associated with lung pathology and severe COVID-19

Mast cell activation in lungs during SARS-CoV-2 infection associated with lung pathology and severe COVID-19

Janessa Y.J. Tan,1 Danielle E. Anderson,2,3 Abhay P.S. Rathore,4 Aled O’Neill,1 Chinmay Kumar Mantri,1 Wilfried A.A. Saron,1 Cheryl Q.E. Lee,5 Chu Wern Cui,5 Adrian E.Z. Kang,1 Randy Foo,1 Shirin Kalimuddin,1,6 Jenny G. Low,1,6 Lena Ho,5 Paul Tambyah,7,8 Thomas W. Burke,9 Christopher W. Woods,9,10 Kuan Rong Chan,1 Jörn…[...]

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Posted on | Posted on John Murphy | Leave a Comment on Beyond epithelial damage: vascular and endothelial contributions to idiopathic pulmonary fibrosis

Beyond epithelial damage: vascular and endothelial contributions to idiopathic pulmonary fibrosis

James May, Jane A. Mitchell, and R. Gisli Jenkins, Published September 15, 2023 - 10.1172/JCI172058 Idiopathic pulmonary fibrosis (IPF) is a progressive scarring disease of the lung with poor survival. The incidence and…[...]

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Posted on | Posted on John Murphy | Leave a Comment on SARS-CoV-2 particles promote airway epithelial differentiation and ciliation

SARS-CoV-2 particles promote airway epithelial differentiation and ciliation

Julian Gonzalez-Rubio1* Vu Thuy Khanh Le-Trilling2 Lea Baumann1 Maria Cheremkhina1 Hannah Kubiza1 Anja E. Luengen1, 3 Sebastian Reuter3 Christian Taube3 Stephan Ruetten4 Daniela Duarte Campos5 Christian Cornelissen6 Mirko Trilling2 Anja Lena Thiebes1* Front. Bioeng. Biotechnology. , Sec. Tissue Engineering and Regenerative Medicine,…[...]

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Posted on | Posted on John Murphy | Leave a Comment on Molecular mechanisms of COVID-19-induced pulmonary fibrosis and epithelial-mesenchymal transition

Molecular mechanisms of COVID-19-induced pulmonary fibrosis and epithelial-mesenchymal transition

Authors: Peng Pi1† Zhipeng Zeng1† Liqing Zeng1 Bing Han1 Xizhe Bai2 Shousheng Xu3*Front. Pharmacol., 03 August 2023, Sec. Respiratory Pharmacology, Volume 14 - 2023 | https://doi.org/10.3389/fphar.2023.1218059 As the outbreak of COVID-19 caused by severe acute respiratory…[...]

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