Authors: WebMD If you have COVID-19, the illness that comes from infection with the recently discovered coronavirus, your symptoms may be relatively mild and manageable at home. That’s true for most people. But if you’re older or have another illness such as diabetes or heart disease, you’re more at risk for the serious form of COVID-19. Some people — about 1 […]
Authors: NIH Interferons are a family of cytokines with antiviral properties. They have been suggested as a potential treatment for COVID-19 because of their in vitro and in vivo antiviral properties. Recommendation The COVID-19 Treatment Guidelines Panel recommends against the use of interferons for the treatment of patients with severe or critical COVID-19, except in a clinical trial (AIII). There is insufficient evidence to […]
Authors: David C. Fajgenbaum, M.D., and Carl H. June, M.D. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has reminded us of the critical role of an effective host immune response and the devastating effect of immune dysregulation. This year marks 10 years since the first description of a cytokine storm that developed after chimeric […]
Author: Christina Aungst, PharmD Key takeaways: People who were sick with COVID-19 and recovered might have long-term immunity that lasts for months or years. We don’t know how long vaccine immunity lasts yet, but it is much safer to gain immunity from the vaccine than from getting COVID-19. Experts believe the vaccine will still work […]
Syndrome coronavirus 2 (SARS-CoV-2) pandemic is causing a second outbreak significantly delaying the hope for the virus’ complete eradication. In the absence of effective vaccines, we need effective treatments with low adverse effects that can treat hospitalized patients with COVID-19 disease. In this study, we determined the existence of SARS-CoV-2-specific T cells within CD45RA– memory T […]
Summary CD4+ T cells help B cells to produce antibodies and help CD8+ T cells to kill virus-infected cells One of the dominant cytokines produced by T cells is interferon gamma, a key player in controlling viral infection – see also [41] Lymphopenia is a main feature of COVID-19 infection, affecting CD4+ T cells, CD8+ […]
The role of T cells in the resolution or exacerbation of COVID-19, as well as their potential to provide long-term protection from reinfection with SARS-CoV-2, remains debated. Nevertheless, recent studies have highlighted various aspects of T cell responses to SARS-CoV-2 infection that are starting to enable some general concepts to emerge. For More Information: https://www.nature.com/articles/s41577-020-0402-6
Much of the study on the immune response to SARS-CoV-2, the novel coronavirus that causes COVID-19, has focused on the production of antibodies. But, in fact, immune cells known as memory T cells also play an important role in the ability of our immune systems to protect us against many viral infections, including—it now appears—COVID-19. An […]
The fully vaccinated have finally been given a “get out of jail free card” from the CDC, while those who suffered through the covid infection remain personae non gratae. The National Institutes of Health published a study on June 18, 2020 of the evidence of protective antibodies in those who have been infected with covid. […]
