Authors: FENGYU ZHANG AND MICHAEL D WATERS Coronavirus disease 19 (COVID-19) caused by infection with a novel severe acute respiratory syndrome virus -2 (SARS-CoV-2) has evolved into a pandemic and a global public health emergency. The viral genomics, host cellular factors, and interactions are critical for establishing a viral infection and developing a related disease. […]
Authors: TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (TGEN) Results from a TGen-led international study suggest that SARS-CoV-2 takes advantage of genetic changes among patients with pre-existing lung diseases. The results of a study by an international scientific team co-led by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggest that — like pouring water atop […]
Authors: This analysis was performed primarily by Matt Olm (mattolm@stanford.edu) in Justin Sonnenburg’s lab at Stanford University and Alex Crits-Christoph (crits-christoph@berkeley.edu) in Jill Banfield’s lab at University of California, Berkeley As viruses replicate within their hosts during infection, they mutate and accrue genetic diversity in their populations. These populations are usually shared as a single […]
Authors: Bolzano research centre In March 2020, thousands of scientists around the world joined forces to investigate the questions at the forefront of the medical debate on the pandemic: what genetic factors influence the severity of Covid-19 infections and why do some people develop a serious illness that requires hospitalisation while others have mild or […]
Authors: Heidi Vella Genome sequencing, big data and artificial intelligence are helping doctors to better understand, treat and hopefully beat Covid-19. The global scientific response to the novel coronavirus pandemic, which so far has killed over 328,000 people worldwide, is unprecedented. On 10 January 2020, nine days after the first cases of suspected Covid-19 were identified, the […]
Authors: Elias Visontay@EliasVisontay What is genomic sequencing? Genomic sequencing analyses the virus sample taken from a diagnosed patient and compares it with other cases. Prior to Covid-19, genomic sequencing has been used in Australia to trace the source of outbreaks of food-borne bacteria and hospital infections. After a Covid-19 test (which gathers saliva from the […]
Authors: Anastasios A. Tsonis, Geli Wang, Lvyi Zhang, Wenxu Lu, Aristotle Kayafas & Katia Del Rio-Tsonis Mathematical approaches have been for decades used to probe the structure of nucleotide sequences. This has led to the development of Bioinformatics. In this exploratory work, a novel mathematical method is applied to probe the genetic structure of two related viral families: those of coronaviruses […]
Authors: Melanie Newman, freelance journalist Many patients with “long” covid are experiencing extreme fatigue, a situation that has re-polarised approaches to treatment and rehabilitation. Melanie Newman reports “I submitted the first positive trial of cognitive behavioural therapy [CBT] as a treatment for chronic fatigue in the ’90s,” recalls Michael Sharpe, a professor of psychological medicine who was […]
Authors: Meredith Deliso “Throughout pandemics, the psychological footprint is often way bigger than the medical footprint,” Dr. Claude Mellins, a medical psychologist who co-leads a pandemic initiative called CopeColumbia for the Columbia University Irving Medical Center community, told ABC News. One of the challenges is the pandemic makes it hard to turn to our normal […]
Authors: Rajeswari Parasa When TNM spoke to doctors about the post-recovery phase, they say it takes anywhere between four to twelve weeks for a patient to recover from the symptoms of COVID-19. Doctors suggest that people should limit themselves to doing only mild muscle strengthening and breathing exercises. And that anything beyond mild exercises would […]