Posted on | Posted on John Murphy | Leave a Comment on Use of DAMPs and SAMPs as Therapeutic Targets or Therapeutics: A Note of Caution

Use of DAMPs and SAMPs as Therapeutic Targets or Therapeutics: A Note of Caution

2020 Jun;24(3):251-262. doi: 10.1007/s40291-020-00460-z. Walter Gottlieb Land 1 2 PMID: 32248387 PMCID: PMC7127836 DOI: 10.1007/s40291-020-00460-z Free PMC article Abstract This opinion article discusses the increasing attention paid to the role of activating damage-associated molecular patterns (DAMPs)…[...]

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Posted on | Posted on John Murphy | Leave a Comment on Role of DAMPs in respiratory virus-induced acute respiratory distress syndrome—with a preliminary reference to SARS-CoV-2 pneumonia

Role of DAMPs in respiratory virus-induced acute respiratory distress syndrome—with a preliminary reference to SARS-CoV-2 pneumonia

Review Article; Published: 17 June 2021 Authors: Walter Gottlieb Land Genes & Immunity volume 22, pages141–160 (2021 )Cite this article Abstract When surveying the current literature on COVID-19, the “cytokine storm” is considered to be…[...]

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Posted on | Posted on John Murphy | Leave a Comment on Evolution of NETosis markers and DAMPs have prognostic value in critically ill COVID-19 patients

Evolution of NETosis markers and DAMPs have prognostic value in critically ill COVID-19 patients

Authors: Joram Huckriede, Sara Bülow Anderberg, Albert Morales, Femke de Vries, Michael Hultström, Anders Bergqvist, José T. Ortiz-Pérez, Jan Willem Sels, Kanin Wichapong, Miklos Lipcsey, Marcel van de Poll, Anders Larsson, Tomas Luther, Chris Reutelingsperger, Pablo Garcia de Frutos, Robert Frithiof & Gerry A. F. Nicolaes  Scientific…[...]

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Posted on | Posted on John Murphy | Leave a Comment on Vaccines show declining effectiveness against infection overall but strong protection against hospitalization amid delta variant

Vaccines show declining effectiveness against infection overall but strong protection against hospitalization amid delta variant

Authors: Ben Guarino  2 hrs agoLike6 Comments|51 Three studies published Wednesday by the Centers for Disease Control and Prevention show that protection against the coronavirus from vaccines declined in the midsummer…[...]

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Posted on | Posted on John Murphy | Leave a Comment on Long COVID or Post-acute Sequelae of COVID-19 (PASC): An Overview of Biological Factors That May Contribute to Persistent Symptoms

Long COVID or Post-acute Sequelae of COVID-19 (PASC): An Overview of Biological Factors That May Contribute to Persistent Symptoms

Authors: Amy D. Proal1 and Michael B. VanElzakker1,2* The novel virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a pandemic of coronavirus disease 2019 (COVID-19). Across the globe, a subset…[...]

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Posted on | Posted on John Murphy | Leave a Comment on Potential mechanisms of cerebrovascular diseases in COVID-19 patients

Potential mechanisms of cerebrovascular diseases in COVID-19 patients

Authors: Manxue Lou 1, Dezhi Yuan 2 3, Shengtao Liao 4, Linyan Tong 1, Jinfang Li 5Affiliations expand Abstract Since the outbreak of coronavirus disease 2019 (COVID-19) in 2019, it is gaining worldwide attention at the moment. Apart from respiratory manifestations,…[...]

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Posted on | Posted on John Murphy | Leave a Comment on The Impact of the Covid 19 Pandemic on Cerebrovascular Disease: CORD-Papers-2021-06-28

The Impact of the Covid 19 Pandemic on Cerebrovascular Disease: CORD-Papers-2021-06-28

Abstract:            Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes a systemic disease that affects nearly all organ systems through infection and subsequent dysregulation of the vascular endothelium. One of the…[...]

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Posted on | Posted on John Murphy | Leave a Comment on C-Reactive Protein Level May Predict the Risk of COVID-19 Aggravation

C-Reactive Protein Level May Predict the Risk of COVID-19 Aggravation

Authors: Guyi Wang 1, Chenfang Wu 1, Quan Zhang 2, Fang Wu 3, Bo Yu 1, Jianlei Lv 2, Yiming Li 4, Tiao Li 5, Siye Zhang 1, Chao Wu 6 7 8, Guobao Wu 1, Yanjun Zhong 1Affiliations expand Abstract Background: Clinical findings indicated that a fraction of coronavirus disease 2019 (COVID-19) patients diagnosed as mild…[...]

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Posted on | Posted on John Murphy | Leave a Comment on Elevated level of C‐reactive protein may be an early marker to predict risk for severity of COVID‐19

Elevated level of C‐reactive protein may be an early marker to predict risk for severity of COVID‐19

Authors: Nurshad Ali 1 The outbreak of coronavirus disease‐2019 (COVID‐19) is an emerging global health threat. The healthcare workers are facing challenges in reducing the severity and mortality of COVID‐19 across…[...]

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