Scientists explain possible causes of anaphylaxis following mRNA COVID-19 vaccination

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Authors: By Angela Betsaida B. Laguipo, BSN In an effort to stem the spread of the coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogen, vaccination efforts have been implemented in most countries. Two of the vaccines developed to prevent SARS-CoV-2 infection are the novel messenger ribonucleic acid (mRNA) […]

Anaphylaxis is a rare reaction in COVID-19 vaccination

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Authors: R G Bellomo 1, C E Gallenga 2, Al Caraffa 3, G Tetè 4, G Ronconi 5, P Conti 6 Abstract Anaphylaxis is a severe multisystem reaction that occurs rapidly after the introduction of an antigen that would otherwise be a harmless substance. It is characterized by airway and respiratory problems, cardiovascular collapse, mucosal inflammation, and other complications, all severe symptoms that can cause death. […]

Interim Considerations: Preparing for the Potential Management of Anaphylaxis after COVID-19 Vaccination

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Authors: CDC Summary of recent changes (last updated March 3, 2021) Considerations broadened to include use of Janssen (Johnson & Johnson) COVID-19 vaccine. Key Points Under the Emergency Use Authorizationsexternal icon for COVID-19 vaccines, appropriate medical treatment for severe allergic reactions must be immediately available in the event that an acute anaphylactic reaction occurs following administration of […]

FDA Authorizes Covid Booster Shots For Immunocompromised Patients

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Authors: BY TYLER DURDEN After growing chatter over the past week, late on Thursday the U.S. Food and Drug Administration authorized booster shots for certain people with weakened immune systems, likely the launch of broader efforts to better protect against evasive variants like Delta. The agency said that other fully vaccinated individuals do not need […]

Children born during pandemic have lower IQs, US study finds

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Authors: Natalie Grover Science correspondent Children born during the coronavirus pandemic have significantly reduced verbal, motor and overall cognitive performance compared with children born before, a US study suggests. The first few years of a child’s life are critical to their cognitive development. But with Covid-19 triggering the closure of businesses, nurseries, schools and playgrounds, life […]

Deadly Lambda variant could be vaccine-resistant, new study says

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Authors: By Hannah Sparks As the US struggles to suppress the rapidly advancing coronavirus Delta variant, new evidence has emerged that the latest Lambda mutation — ravaging parts of South America — won’t be slowed by vaccines. In a July 28 report appearing on bioRxiv, where the study awaits peer review prior to getting published, researchers in […]

Huge study supporting ivermectin as Covid treatment withdrawn over ethical concerns

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The preprint endorsing ivermectin as a coronavirus therapy has been widely cited, but independent researchers find glaring discrepancies in the data Authors: Melissa Davey The efficacy of a drug being promoted by rightwing figures worldwide for treating Covid-19 is in serious doubt after a major study suggesting the treatment is effective against the virus was […]

Ivermectin: a systematic review from antiviral effects to COVID-19 complementary regimen

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Authors: Fatemeh Heidary 1, Reza Gharebaghi 2 3 Abstract Ivermectin proposes many potentials effects to treat a range of diseases, with its antimicrobial, antiviral, and anti-cancer properties as a wonder drug. It is highly effective against many microorganisms including some viruses. In this comprehensive systematic review, antiviral effects of ivermectin are summarized including in vitro and in vivo studies […]

A five-day course of ivermectin for the treatment of COVID-19 may reduce the duration of illness

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Authors: Sabeena Ahmed 1, Mohammad Mahbubul Karim 1, Allen G Ross 1, Mohammad Sharif Hossain 1, John D Clemens 1, Mariya Kibtiya Sumiya 1, Ching Swe Phru 1, Mustafizur Rahman 1, Khalequ Zaman 1, Jyoti Somani 2, Rubina Yasmin 3, Mohammad Abul Hasnat 4, Ahmedul Kabir 5, Asma Binte Aziz 1, Wasif Ali Khan 6 Abstract Ivermectin, a US Food and Drug Administration-approved anti-parasitic agent, was found to inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication in vitro. A randomized, double-blind, placebo-controlled trial […]

Ivermectin for Prevention and Treatment of COVID-19 Infection: A Systematic Review, Meta-analysis, and Trial Sequential Analysis to Inform Clinical Guidelines

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Authors: Andrew Bryant, MSc,1,* Theresa A. Lawrie, MBBCh, PhD,2 Therese Dowswell, PhD,2 Edmund J. Fordham, PhD,2 Scott Mitchell, MBChB, MRCS,3 Sarah R. Hill, PhD,1 and Tony C. Tham, MD, FRCP4 Background: Repurposed medicines may have a role against the SARS-CoV-2 virus. The antiparasitic ivermectin, with antiviral and anti-inflammatory properties, has now been tested in numerous clinical trials. Areas of uncertainty: We assessed […]