Category: Autoimmune Disease

Evolution of NETosis markers and DAMPs have prognostic value in critically ill COVID-19 patients

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Authors: Joram Huckriede, Sara Bülow Anderberg, Albert Morales, Femke de Vries, Michael Hultström, Anders Bergqvist, José T. Ortiz-Pérez, Jan Willem Sels, Kanin Wichapong, Miklos Lipcsey, Marcel van de Poll, Anders Larsson, Tomas Luther, Chris Reutelingsperger, Pablo Garcia de Frutos, Robert Frithiof & Gerry A. F. Nicolaes  Scientific Reports volume 11, Article number: 15701 (2021) Cite this article Abstract Coronavirus disease 19 (COVID-19) presents with disease severities of varying degree. In its most severe form, infection may lead to […]

ABO blood group and COVID-19: a review on behalf of the ISBT COVID-19 working group

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Authors: the ISBT COVID-19 Working Group School of Medicine Abstract Growing evidence suggests that ABO blood group may play a role in the immunopathogenesis of SARS-CoV-2 infection, with group O individuals less likely to test positive and group A conferring a higher susceptibility to infection and propensity to severe disease. The level of evidence supporting […]

No point vaccinating those who’ve had COVID-19: Cleveland Clinic study suggests

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Authors: By Dr. Sanchari Sinha Dutta, Ph.D.Jun 8 2021 Scientists from the Cleveland Clinic, USA, have recently evaluated the effectiveness of coronavirus disease 2019 COVID-19) vaccination among individuals with or without a history of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The study findings reveal that individuals with previous SARS-CoV-2 infection do not get additional […]

Mapping the human genetic architecture of COVID-19

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COVID-19 Host Genetics Initiative, Nature (2021) Abstract The genetic makeup of an individual contributes to susceptibility and response to viral infection. While environmental, clinical and social factors play a role in exposure to SARS-CoV-2 and COVID-19 disease severity1,2, host genetics may also be important. Identifying host-specific genetic factors may reveal biological mechanisms of therapeutic relevance and […]

Simple blood test can tell whether patients will suffer from ‘long COVID’

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Authors: by Study Finds AUGUST 15, 2021 CAMBRIDGE, England — A simple blood test for long COVID is on the horizon. Biological “fingerprints” can identify individuals with the debilitating syndrome, according to new research. This opens the door to the first accurate diagnosis of the mysterious condition. Sufferers complain it is hard to convince doctors of […]

Resolving “Long-Haul COVID” and Vaccine Toxicity: Neutralizing the Spike Protein

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Authors: Dr. Thomas E. Levy, MD, JD July 1, 2021 Although the mainstream media outlets might have you believe otherwise, the vaccines that continue to be administered for the COVID pandemic are emerging as substantial sources of morbidity and mortality themselves. While the degree to which these negative outcomes of the COVID vaccines can be debated, […]

Long COVID and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)—A Systemic Review and Comparison of Clinical Presentation and Symptomatology

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Authors: Timothy L. Wong* and Danielle J. Weitzer Abstract Background and Objectives: Long COVID defines a series of chronic symptoms that patients may experience after resolution of acute COVID-19. Early reports from studies with patients with long COVID suggests a constellation of symptoms with similarities to another chronic medical illness—myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). A review study comparing […]

Inflammatory brain injury higher in men with acute COVID-19, finds study

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Download PDF Copy Authors: By Dr. Liji Thomas, MD The coronavirus disease 2019 (COVID-19) pandemic has been associated with both short- and long-term neurologic complications, including stroke, brain fog and persistent tiredness. A new study concludes that the effects of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on the central nervous system are due to the […]

Coronavirus and the Nervous System

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Authors: The U.S. Centers for Disease Control and Prevention What do we know about the effects of SARS-CoV-2 and COVID-19 on the nervous system? Much of the research to date has focused on the acute infection and saving lives. These strategies have included preventing infection with vaccines, treating COVID-19 symptoms with medicines or antibodies, and […]

Trained Innate Immunity, Epigenetics, and Covid-19

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Authors: Alberto Mantovani, M.D., and Mihai G. Netea, M.D. Innate immunity is mediated by different cell types and cell-associated or fluid-phase pattern-recognition molecules and plays a key role in tissue repair and resistance against pathogens.1 Exposure to selected vaccines, such as bacille Calmette–Guérin (BCG) or microbial components, can increase the baseline tone of innate immunity and trigger […]