Immune system shifts may explain why some long COVID patients struggle to breathe

by University of Virginia Unsupervised analysis reveals clinical phenotypes of pulmonary disease. Credit: Nature Immunology (2025). DOI: 10.1038/s41590-025-02110-0 Research from the University of Virginia School of Medicine has revealed crucial new insights into…[...]

Read More

đŸ« Long COVID and Gas Exchange Dysfunction: Interstitial Fibrosis, Therapeutic Strategies, and Reversibility

Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), continues to affect millions globally, with shortness of breath and impaired gas exchange among its most persistent symptoms. Recent peer-reviewed studies…[...]

Read More

A GABA-receptor agonist reduces pneumonitis severity, viral load, and death rate in SARS-CoV-2-infected mice

Jide Tian1*Barbara J. Dillion2Jill Henley3et. al. Gamma-aminobutyric acid (GABA) and GABA-receptors (GABA-Rs) form a major neurotransmitter system in the brain. GABA-Rs are also expressed by 1) cells of the innate…[...]

Read More

Postacute Sequelae of SARS-CoV-2 Infection in the Pre-Delta, Delta, and Omicron Eras

Authors: Yan Xie, Ph.D. https://orcid.org/0000-0002-2457-9382, Taeyoung Choi, M.S., and Ziyad Al-Aly, M.D. https://orcid.org/0000-0002-2600-0434, N Engl J Med 2024;391:515-525, DOI: 10.1056/NEJMoa2403211, VOL. 391 NO. 6 Abstract Background Postacute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (PASC) can affect many organ systems. However, temporal…[...]

Read More