Category: Vaccine News

[caption id="attachment_106" align="alignnone" width="240"]                    Vaccine News[/caption]

Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line

Posted on | Posted on John Murphy | Leave a Comment on Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line

Authors:  Markus Aldén 1,Francisko Olofsson Falla 1,Daowei Yang 1,Mohammad Barghouth 1,Cheng Luan 1,Magnus Rasmussen 2 andYang De Marinis 1,*1Department of Clinical Sciences, Lund University, 20502 Malmö, Sweden2Infection Medicine, Department of Clinical Sciences, Lund University, 22362 Lund, Sweden Abstract Preclinical studies of COVID-19 mRNA vaccine BNT162b2, developed by Pfizer and BioNTech, showed reversible hepatic effects in animals that received the BNT162b2 injection. Furthermore, a […]

Protection against Covid-19 by BNT162b2 Booster across Age Groups

Posted on | Posted on John Murphy | Leave a Comment on Protection against Covid-19 by BNT162b2 Booster across Age Groups

Authors. Yinon M. Bar-On, M.Sc., Yair Goldberg, Ph.D., Micha Mandel, Ph.D., Omri Bodenheimer, M.Sc., Laurence Freedman, Ph.D., Sharon Alroy-Preis, M.D., Nachman Ash, M.D., Amit Huppert, Ph.D., and Ron Milo, Ph.D. Abstract BACKGROUND After promising initial results from the administration of a third (booster) dose of the BNT162b2 messenger RNA vaccine (Pfizer–BioNTech) to persons 60 years of age or older, the booster campaign in […]

COVID-19 vaccination followed by activation of glomerular diseases: does association equal causation?

Posted on | Posted on John Murphy | Leave a Comment on COVID-19 vaccination followed by activation of glomerular diseases: does association equal causation?

Authors: Nicholas L. Li,1P. Toby Coates,2 and Brad H. Rovin1,∗ Kidney Int. 2021 Nov; 100(5): 959–965.Published online 2021 Sep 14. doi: 10.1016/j.kint.2021.09.002 PMCID: PMC8437826PMID: 34534551 To date, >4 billion doses of the various severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines have been administered worldwide in response to the coronavirus disease 2019 (COVID-19) pandemic. Even as widespread vaccination campaigns have contributed to […]

Age- and Sex-Specific Incidence of Cerebral Venous Sinus Thrombosis Associated With Ad26.COV2.S COVID-19 Vaccination

Posted on | Posted on John Murphy | Leave a Comment on Age- and Sex-Specific Incidence of Cerebral Venous Sinus Thrombosis Associated With Ad26.COV2.S COVID-19 Vaccination

Authors: Aneel A. Ashrani, MD, MS1; Daniel J. Crusan, BS2; Tanya Petterson, MS2; et al JAMA Intern Med. 2022;182(1):80-83. doi:10.1001/jamainternmed.2021.6352 Recent reports1–4 suggest a possible association between Ad26.COV2.S (Johnson & Johnson/Janssen) COVID-19 vaccination and cerebral venous sinus thrombosis (CVST). Estimates of postvaccination CVST risk require accurate age- and sex-specific prepandemic CVST incidence rates; however, reported rates vary widely.5 We compared the age- and sex-specific CVST rates after […]

Pfizer BioNTech Covid Vaccine and Ovarian cysts – a phase IV clinical study of CDC and FDA data

Posted on | Posted on John Murphy | Leave a Comment on Pfizer BioNTech Covid Vaccine and Ovarian cysts – a phase IV clinical study of CDC and FDA data

Summary: Ovarian cysts is found among people who get Pfizer BioNTech Covid Vaccine, especially for people who are 30-39 old, and after 30 days of getting the vaccine. The phase IV clinical study analyzes which people get Pfizer BioNTech Covid Vaccine and have Ovarian cysts. It is created by eHealthMe based on reports of 286,220 […]

Association of Myocarditis With BNT162b2 Messenger RNA COVID-19 Vaccine in a Case Series of Children

Posted on | Posted on John Murphy | Leave a Comment on Association of Myocarditis With BNT162b2 Messenger RNA COVID-19 Vaccine in a Case Series of Children

Authors: Audrey Dionne, MD1,2; Francesca Sperotto, MD1,2; Stephanie Chamberlain1,2; et alAnnette L. Baker, MSN, CPNP1,2; Andrew J. Powell, MD1,2; Ashwin Prakash, MD1,2; Daniel A. Castellanos, MD1,2; Susan F. Saleeb, MD1,2; Sarah D. de Ferranti, MD, MPH1,2; Jane W. Newburger, MD, MPH1,2; Kevin G. Friedman, MD1,2 JAMA Cardiol. 2021;6(12):1446-1450. doi:10.1001/jamacardio.2021.347 Question  What are the findings on cardiac imaging in children with myocarditis after COVID-19 vaccination? Findings  In this case series of 15 children who were hospitalized with myocarditis after receipt of the BNT162b2 messenger RNA COVID-19 vaccine for 1 to […]

Study: Myocarditis risk 37 times higher for children with COVID-19 than uninfected peers

Posted on | Posted on John Murphy | Leave a Comment on Study: Myocarditis risk 37 times higher for children with COVID-19 than uninfected peers

Authors: Melissa Jenco, News Content Editor August 31, 2021 The risk of myocarditis for children under 16 years is 37 times higher for those infected with COVID-19 than those who haven’t been infected with the virus, according to a new study. Authors from the Centers for Disease Control and Prevention (CDC) said the study provides […]

The potential for antibody-dependent enhancement of SARS-CoV-2 infection: Translational implications for vaccine development

Posted on | Posted on John Murphy | Leave a Comment on The potential for antibody-dependent enhancement of SARS-CoV-2 infection: Translational implications for vaccine development

Authors:  Jiong Wang andMartin S. Zand Published online by Cambridge University Press: 13 April 2020 Journal of Clinical and Translational Science>Volume 5 Issue 1 Abstract There is an urgent need for vaccines to the 2019 coronavirus (COVID19; SARS-CoV-2). Vaccine development may not be straightforward, due to antibody-dependent enhancement (ADE). Antibodies against viral surface proteins can, in some […]