Vaccine-induced immune thrombotic thrombocytopenia

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BLOOD SPOTLIGHT| APRIL 6, 2023 Douglas B. Cines, Andreas Greinacher Blood (2023) 141 (14): 1659–1665. https://doi.org/10.1182/blood.2022017696 Within the first months of the COVID-19 vaccination campaign, previously healthy recipients who developed severe thrombosis (often cerebral and/or splanchnic vasculature) and thrombocytopenia typically after adenoviral vector-based vaccination were identified. Similarities between this syndrome, vaccine-induced immune thrombotic thrombocytopenia (VITT), and heparin-induced […]

COVID-19 and possible links with Parkinson’s disease and parkinsonism: from bench to bedside

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David Sulzer, Angelo Antonini, Valentina Leta, Anna Nordvig, Richard J. Smeyne, James E. Goldman, Osama Al-Dalahmah, Luigi Zecca, Alessandro Sette, Luigi Bubacco, Olimpia Meucci, Elena Moro, Ashley S. Harms, Yaqian Xu, Stanley Fahn & K. Ray Chaudhuri  npj Parkinson’s Disease volume 6, Article number: 18 (2020) Cite this article Abstract This Viewpoint discusses insights from basic science and clinical perspectives on coronavirus disease 2019 (COVID-19)/severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection in the brain, with a particular focus […]

COVID-19 can trigger auto-immune disorders-related antibodies, causing thrombosis and other complications

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SEPTEMBER 12, 2023 by Maria Fernanda Ziegler, FAPESP Medical Express An article published in npj Aging reveals that natural production of auto-antibodies increases with age, and that infection by SARS-CoV-2 can exacerbate production of auto-antibodies relating to auto-immune diseases, helping to explain why aging increases the chances of developing severe COVID-19. The study also discovered some of the factors that […]

Detrimental effects of COVID-19 in the brain and therapeutic options for long COVID: The role of Epstein–Barr virus and the gut–brain axis

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Kenji Hashimoto, Molecular Psychiatry (2023) Published: 04 July 2023 Abstract The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in a serious public health burden worldwide. In addition to respiratory, heart, and gastrointestinal symptoms, patients infected with SARS-CoV-2 experience a number of persistent neurological and psychiatric symptoms, known as […]

Large COVID autopsy study finds SARS-CoV-2 all over the human body

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By Rich Haridy January 04, 2023 Source: National Institute of Allergy and Infectious Diseases A study found traces of the SARS-CoV-2 virus in over 80 different sites in the body In the most comprehensive autopsy tissue study conducted to date, researchers have found traces of the SARS-CoV-2 virus throughout the entire body, from the brain and the […]

Vagus nerve inflammation contributes to dysautonomia in COVID-19

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Marcel S Woo 1, Mohsin Shafiq 2, Antonia Fitzek 3, Matthias Dottermusch 2, Hermann Altmeppen 2, Behnam Mohammadi 2, Christina Mayer 1, Lukas C Bal 1, Lukas Raich 1, Jakob Matschke 2, Susanne Krasemann 2, Susanne Pfefferle 4, Thomas Theo Brehm 5 6, Marc Lütgehetmann 4, Julia Schädler 3, Marylyn M Addo 5 6 7, Julian Schulze Zur Wiesch 5 6, Benjamin Ondruschka 3, Manuel A Friese # 8, Markus Glatzel # 9 PMID: 37452829 PMCID: PMC10412500 DOI: 10.1007/s00401-023-02612-x Abstract Dysautonomia has substantially impacted acute COVID-19 severity as well as symptom burden after recovery from COVID-19 (long COVID), yet the underlying causes remain […]

Persistent Brainstem Dysfunction in Long-COVID: A Hypothesis

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Shin Jie Yong PMID: 33538586 DOI: 10.1021/acschemneuro.0c00793 ACS Chem Neuroscience . 2021 Feb 17;12(4):573-580. doi: 10.1021/acschemneuro.0c00793. Epub 2021 Feb 4. Abstract Long-COVID is a postviral illness that can affect survivors of COVID-19, regardless of initial disease severity or age. Symptoms of long-COVID include fatigue, dyspnea, gastrointestinal and cardiac problems, cognitive impairments, myalgia, and others. While the possible causes of long-COVID include […]

Study: With each Covid vaccination, healthcare workers get sicker – applying for progressively more leave and taking more analgesic medication after each dose

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EUGYPPIUS, SEP 20, 2023 eugyppius: a plague chronicle “Inability to work following COVID-19 vaccination” is a modest paper just published in Public Health, analyzing data from the ‘CoVacSer’ cohort study, conducted out of Würzburg to monitor the effects of Covid infection and vaccination on healthcare workers. Of 1,831 CoVacSer participants who were surveyed on their experiences […]

What you need to know about Covid as new variant rises

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September 24, 2023 BBC News Jim Reed The number of people in hospital has gone up. Google searches have doubled in a month and booster vaccines have been brought forward because of a new variant. It might all feel a bit 2021. But – these days – how much do we really need to worry […]

Lingering COVID virus in tongue linked to long-term taste loss

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August 24, 2023 National Institute on Aging: National Institutes of Health Loss of taste, one of the most common and frustrating symptoms of COVID-19 infection, appears to be associated with persistent damage to taste buds caused by low amounts of the virus that can linger for months or even more than a year. Findings from […]