Domains and Functions of Spike Protein in SARS-Cov-2 in the Context of Vaccine Design


Authors: Xuhua Xia1,2Kenneth Lundstrom, Academic Editor and Alaa. A. A. Aljabali, Academic Editor Abstract The spike protein in SARS-CoV-2 (SARS-2-S) interacts with the human ACE2 receptor to gain entry into a cell to initiate infection. Both Pfizer/BioNTech’s BNT162b2 and Moderna’s mRNA-1273 vaccine candidates are based on stabilized mRNA encoding prefusion SARS-2-S that can be produced after the mRNA […]

Long-Term Dangers Of Experimental mRNA Shots


Authors: Analysis by Dr. Joseph Mercola STORY AT-A-GLANCE mRNA-based COVID shots have used codon optimization to improve protein production. A codon consists of three nucleotides, and nucleotides are the building blocks of DNA. Use of codon optimization virtually guarantees unexpected results Replacing rare codons must be done judiciously, as rarer codons can have slower translation rates […]

Early Omicron Breakthroughs Show MRNA Vaccines’ Weakness


Authors: Antony Sguazzin Copyright © Bloomberg (Bloomberg) — Booster shots with messenger RNA vaccines such as those made by Pfizer Inc. and BioNTech SE failed to block omicron in a study of some of the first documented breakthrough cases caused by the highly contagious variant. Seven German visitors to Cape Town experienced symptomatic Covid-19 infections […]

New data show those who recovered from Covid-19 were less likely than vaccinated to get infected during Delta wave


Authors: Andrew Joseph  Jan. 19, 2022 New data released Wednesday showed that both vaccination and prior infection offered strong protection against infection and hospitalization from Covid-19 during the Delta wave — and that case and hospitalization rates were actually lower among people who had recovered from Covid-19 than among those who had been vaccinated. The […]

COVID-19 and chronic kidney disease: a comprehensive review


Authors: Inah Maria D. Pecly,1Rafael B. Azevedo,1Elizabeth S. Muxfeldt,1,2Bruna G. Botelho,1Gabriela G. Albuquerque,1Pedro Henrique P. Diniz,1Rodrigo Silva,1 and Cibele I. S. Rodrigues3 J Bras Nefrol. 2021 Jul-Sep; 43(3): 383–399.Published online 2021 Apr 9. doi: 10.1590/2175-8239-JBN-2020-0203PMCID: PMC8428633PMID: 33836039 Abstract Kidney impairment in hospitalized patients with SARS-CoV-2 infection is associated with increased in-hospital mortality and worse clinical evolution, raising concerns towards patients with chronic […]

4 Ways COVID Leaves Its Mark on the Eye


Authors: Reena MukamalReviewed By Joseph T Nezgoda, MD MBA Sep. 14, 2021 An analysis of 121 patients dating back to the beginning of the pandemic unveils COVID’s most common effects on the eye. Share this information and remember: Widespread vaccination is key to ending the pandemic. How does COVID reach the eyes? People respond in different ways to COVID-19 infections. While […]

Ophthalmic Manifestations Of Coronavirus (COVID-19)


Authors: Katherine Hu; Jay Patel; Cole Swiston; Bhupendra C. Patel. Introduction Since December 2019, coronavirus disease 2019 (COVID-19) has become a global pandemic caused by the highly transmissible severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).[1] Initially, there were several reports of eye redness and irritation in COVID-19 patients, both anecdotal and published, supporting conjunctivitis as an ocular manifestation of SARS-CoV-2 infection. Reports […]

Gastrointestinal perforation secondary to COVID-19


Authors: Case reports and literature review Reem J. Al Argan, MBBS, SB-Med, SF-Endo, FACE, ECNU,∗Safi G. Alqatari, MBBS, MRCPI, MMedSc, CFP (Rheum), Abir H. Al Said, MBBS, SB-Med, CFP (Pulmo.), Raed M. Alsulaiman, MBBS, SB-Med, Abdulsalam Noor, MBBS, SB-Med, ArBIM, SF-Nephro, Lameyaa A. Al Sheekh, MD, SB-med, and Feda’a H. Al Beladi, MD Introduction: Corona virus disease-2019 (COVID-19) presents primarily […]

Side effects of BNT162b2 mRNA COVID-19 vaccine: A randomized, cross-sectional study with detailed self-reported symptoms from healthcare workers


Authors: Renuka A.K. Kadali,a,b,1,⁎Ravali Janagama,c,1,⁎⁎Sharanya Peruru,d and Srikrishna V. Malayalae Int J Infect Dis. 2021 May; 106: 376–381.Published online 2021 Apr 15. doi: 10.1016/j.ijid.2021.04.047 Abstract Introduction Concerns are prevailing about the safety and side effects of the BNT162b2 mRNA vaccine for coronavirus disease 2019 (COVID-19). Methods A randomized, cross-sectional study was performed to investigate the side effects of the BNT162b2 […]