Pathophysiological, immunological, and inflammatory features of long COVID

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Karen Bohmwald1,2†Benjamín Diethelm-Varela1†Linmar Rodríguez-Guilarte1, et. al. Front. Immunol., 27 February 2024, Volume 15 – 2024, https://doi.org/10.3389/fimmu.2024.1341600 The COVID-19 pandemic continues to cause severe global disruption, resulting in significant excess mortality, overwhelming healthcare systems, and imposing substantial social and economic burdens on nations. While most of the attention and therapeutic efforts have concentrated on the acute […]

The Prevalence of Dizziness and Vertigo in COVID-19 Patients: A Systematic Review

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George Korres,1,* Dimitrios K. Kitsos,2 Diego Kaski,3 et. al. Abstract Clinical manifestations of COVID-19 include symptoms of vertigo and dizziness, which is rather unsurprising, since SARS-CoV-2 neurotropism may inflict a broad spectrum of neuropathic effects. The widespread nature of central and peripheral audiovestibular pathways suggests that there may be several probable pathophysiological mechanisms. The cytokine storm, CNS infiltration […]

The knowns and unknowns of long COVID-19: from mechanisms to therapeutical approaches

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Roxana Gheorghita1,2Iuliana Soldanescu3Andrei Lobiuc2, et. al. University of Medicine and Pharmacy, Timisoara, Romania The coronavirus disease 2019 (COVID-19) pandemic caused by SARS-CoV-2 has been defined as the greatest global health and socioeconomic crisis of modern times. While most people recover after being infected with the virus, a significant proportion of them continue to experience health […]

Neurological Complications of COVID-19 Infection: A Comprehensive Review

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Travis Brauer • Sulaiman Paika • Roshni Kotwani • Deepesh Khanna, 2024, DOI: 10.7759/cureus.65192  Abstract The COVID-19 pandemic is well on its way to reaching endemic status across the globe. While the medical community’s understanding of the respiratory complications induced by COVID-19 is improving, there is still much to be learned about the neurological manifestations associated with COVID-19 infection. This review aimed […]

Liver injury in COVID-19: an insight into pathobiology and roles of risk factors

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Abbas Tazarghi, Sahar Bazoq, Mohammad Hosein Taziki Balajelini, et. al. Virology Journal volume 21, Article number: 65 (2024)  Abstract COVID-19 is a complex disease that can lead to fatal respiratory failure with extrapulmonary complications, either as a direct result of viral invasion in multiple organs or secondary to oxygen supply shortage. Liver is susceptible to many viral pathogens, and due to its […]

Long-Term Taste and Smell Outcomes After COVID-19

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Ryan Sharetts, BS1,2; Shima T. Moein, MD, PhD1,2; Rafa Khan, BS1; et alRichard L. Doty, PhD1, JAMA Netw Open. 2024;7(4):e247818. doi:10.1001/jamanetworkopen.2024.7818 Key Points Question  What is the association of COVID-19 with long-term outcomes in taste and smell function as measured by state-of-the-art psychophysical tests? Findings  In this cross-sectional study of 340 individuals with and 434 individuals without prior COVID-19, taste function did not differ between individuals who had contracted […]

How To Manage COVID Fatigue and Regain Your Energy

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It’s important to connect with a healthcare provider, get quality sleep and balance your activities with your energy levels You had COVID-19 a few weeks or even months ago. But you’re still dealing with the symptoms of the infection, like fatigue and shortness of breath. Advertisement Cleveland Clinic is a non-profit academic medical center. Advertising on our […]

Is Low-Dose Lung Radiotherapy for Severe COVID-19 Pneumonia a Therapeutic Alternative?

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Fatima Safini • Bouchra Amaoui • Kenza Oqbani • et. al. , 2024DOI: 10.7759/cureus.6503 Abstract Low-dose radiotherapy (LD-RT) has historically been used to treat severe bacterial and viral pneumonia due to its immunomodulatory properties. However, this technique has been delayed since the advent of antibiotics and the carcinogenic risk associated with radiation therapy. Currently, it represents an alternative therapeutic in the SARS-CoV-2 […]

Nerve Palsy With Positive Asialo-GM1 Antibody After SARS-CoV-2 mRNA Vaccination

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Ifeanyichukwu Ozobu • Ethan Salter • Sophia Salter • et. al. 2024DOI: 10.7759/cureus.65045  Abstract mRNA vaccines have been a critical tool in combating the current coronavirus disease 2019 (COVID-19) pandemic and demonstrated a high safety profile. However, rare cases of isolated oculomotor nerve palsy following vaccination have been reported. These few reported cases can be divided into two groups based on symptom […]

Researchers discover that tiredness experienced by long COVID patients has a physical cause

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by Amsterdam University Medical Center Researchers from Amsterdam UMC and Vrije Universiteit Amsterdam (VU) have discovered that the persistent fatigue in patients with long COVID has a biological cause, namely mitochondria in muscle cells that produce less energy than in healthy patients. The results of the study were published in Nature Communications. “We’re seeing clear changes in the […]