What’s Sex Got to Do With COVID-19? Gender-Based Differences in the Host Immune Response to Coronaviruses

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Authors: Nirupa Gadi1,2, Samantha C. Wu1,2, Allison P. Spihlman1,2 and Vaishali R. Moulton1* The novel severe acute respiratory syndrome coronavirus 2, the cause of the coronavirus disease 2019 (COVID-19) pandemic, has ravaged the world, with over 22 million total cases and over 770,000 deaths worldwide as of August 18, 2020. While the elderly are most severely affected, implicating an […]

Returning to physical activity after covid-19

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Authors: David Salman, academic clinical fellow in primary care12,  Dane Vishnubala, consultant in sports and exercise medicine and honorary senior lecturer in primary care and public health23,  Peter Le Feuvre, military physiotherapist and research fellow in complex trauma rehabilitation15,  Thomas Beaney, academic clinical fellow in primary care2,  Jonathan Korgaonkar, consultant in sports and exercise medicine4, […]

Pathological findings of COVID-19 associated with acute respiratory distress syndrome

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Authors: Zhe Xu, MD, Lei Shi, MD, Yijin Wang, PhD, Jiyuan Zhang, PhD, Lei Huang, MD, Chao Zhang, PhD, Shuhong Liu, MSc, Peng Zhao, MSc, Hongxia Liu, BSc, Li Zhu, MSc, Yanhong Tai, MD, Prof Changqing Bai, MD. Tingting Gao, BSc,Jinwen Song, PhD, Peng Xia, MSc, Jinghui Dong, MD, Prof Jingmin Zhao, MD , Prof […]

Prevention and Prophylaxis of SARS-CoV-2 Infection

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Authors: NIH The COVID-19 Treatment Guidelines Panel (the Panel) recommends that health care providers follow recommendations from the Advisory Committee on Immunization Practices when using SARS-CoV-2 vaccines (AI).The Panel recommends against the use of any drugs for SARS-CoV-2 pre-exposure prophylaxis (PrEP), except in a clinical trial (AIII).The Panel recommends against the use of hydroxychloroquine for […]

How COVID-19 Spreads

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Authors: CDC COVID-19 spreads when an infected person breathes out droplets and very small particles that contain the virus. These droplets and particles can be breathed in by other people or land on their eyes, noses, or mouth. In some circumstances, they may contaminate surfaces they touch. People who are closer than 6 feet from the infected person are most likely to […]

Respiratory follow-up of patients with COVID-19 pneumonia

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Authors: http://orcid.org/0000-0003-1316-4891Peter M George1,2, http://orcid.org/0000-0003-3067-7349Shaney L Barratt3,4, Robin Condliffe5, Sujal R Desai6, Anand Devaraj6, Ian Forrest7, Michael A Gibbons8, Nicholas Hart9, http://orcid.org/0000-0002-7929-2119R Gisli Jenkins10, Danny F McAuley11, Brijesh V Patel12, Erica Thwaite13, Lisa G Spencer13 The COVID-19 pandemic has led to an unprecedented surge in hospitalised patients with viral pneumonia. The most severely affected patients are older men, individuals of black and Asian minority ethnicity and those […]

Preliminary Findings of mRNA Covid-19 Vaccine Safety in Pregnant Persons

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Authors: Tom T. Shimabukuro, M.D., Shin Y. Kim, M.P.H., Tanya R. Myers, Ph.D., Pedro L. Moro, M.D., Titilope Oduyebo, M.D., Lakshmi Panagiotakopoulos, M.D., Paige L. Marquez, M.S.P.H., Christine K. Olson, M.D., Ruiling Liu, Ph.D., Karen T. Chang, Ph.D., Sascha R. Ellington, Ph.D., Veronica K. Burkel, M.P.H., et al., for the CDC v-safe COVID-19 Pregnancy Registry Team* Many pregnant persons in the United States are receiving messenger RNA (mRNA) […]

Extrapulmonary manifestations of COVID-19

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Authors: Aakriti Gupta, Mahesh V. Madhavan, […]Donald W. Landry Although COVID-19 is most well known for causing substantial respiratory pathology, it can also result in several extrapulmonary manifestations. These conditions include thrombotic complications, myocardial dysfunction and arrhythmia, acute coronary syndromes, acute kidney injury, gastrointestinal symptoms, hepatocellular injury, hyperglycemia and ketosis, neurologic illnesses, ocular symptoms, and dermatologic complications. […]

Filtration Efficiency, Effectiveness, and Availability of N95 Face Masks for COVID-19 Prevention

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Authors: Caitlin M. Dugdale, MD1,2; Rochelle P. Walensky, MD, MPH In March 2020, the soaring number of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections resulted in an unprecedented shortage of personal protective equipment (PPE) for clinicians and essential health care workers.1 The shortage was most profound among N95 masks. N95 respirators, named for their ability to filter 95% or more […]