How does coronavirus kill? Clinicians trace a ferocious rampage through the body, from brain to toes

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Authors: By Meredith Wadman, Jennifer Couzin-Frankel, Jocelyn Kaiser, Catherine MatacicApr. 17, 2020 , 6:45 PM On rounds in a 20-bed intensive care unit one recent day, physician Joshua Denson assessed two patients with seizures, many with respiratory failure and others whose kidneys were on a dangerous downhill slide. Days earlier, his rounds had been interrupted as his team tried, […]

Management of post-acute covid-19 in primary care

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BMJ 2020; 370 doi: https://doi.org/10.1136/bmj.m3026 (Published 11 August 2020)Cite this as: BMJ 2020;370:m3026 Authors: Trisha Greenhalgh, professor of primary care health sciences1,  Matthew Knight, consultant respiratory physician2,  Christine A’Court, general practitioner1,  Maria Buxton, consultant respiratory physiotherapist3,  Laiba Husain, research assistant1 What you need to know Management of covid-19 after the first three weeks is currently based on limited evidence Approximately 10% of […]

Skin rash should be considered as a fourth key sign of COVID-19

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May 22, 2021 Data from the COVID Symptom Study shows that characteristic skin rashes and ‘COVID fingers and toes’ should be considered as key diagnostic signs of the disease, and can occur in the absence of any other symptoms.  The COVID Symptom Study, led by researchers from King’s College London and health science company ZOE, asks participants to log their […]

The Vaccinated Are Worried and Scientists Don’t Have Answers

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Authors: Kristen V. Brown and Rebecca Torrence  14 hrs ago Anecdotes tell us what the data can’t: Vaccinated people appear to be getting the coronavirus at a surprisingly high rate. But exactly how often isn’t clear, nor is it certain how likely they are to spread the virus to others. And now, there’s growing concern that […]

Delta variant likely to bring a fall and winter of masks, vaccine mandates, anxiety

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Authors: Rong-Gong Lin II, Luke Money Fri, August 20, 2021, 8:00 AM The rise of the Delta variant has upended previous optimistic projections of herd immunity and a return to normal life, with many health experts believing mask mandates and tougher vaccine requirements will be needed in the coming months to avoid more serious coronavirus […]

Most face masks won’t stop COVID-19 indoors, study warns

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Authors: by John Anderer New research reveals that cloth masks filter just 10% of exhaled aerosols, with many people not wearing coverings that fit their face properly. WATERLOO, Ontario — N95 or KN95 face masks may be the best way to avoid COVID-19 during crowded indoor events. That’s the recommendation from a new study reporting most […]

Clinical determinants of the severity of COVID-19: A systematic review and meta-analysis

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Authors: Xinyang Li, Xianrui Zhong, Yongbo Wang, Xiantao Zeng, Ting Luo, Qing Liu  Published: May 3, 2021 Abstract Objective We aimed to systematically identify the possible risk factors responsible for severe cases. Methods We searched PubMed, Embase, Web of science and Cochrane Library for epidemiological studies of confirmed COVID-19, which include information about clinical characteristics […]

Analysis of the Study of the Expression of Apoptosis Markers (CD95) and Intercellular Adhesion Markers (CD54) in Healthy Individuals and Patients Who Underwent COVID-19 When Using the Drug Mercureid

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Authors: Sergey N Gusev1*, Velichko LN2, Bogdanova AV2, Khramenko NI2, Konovalova NV2 Published Date: 26-08-2021 Abstract SARS-CoV-2, the pathogen, which is responsible for coronavirus disease 2019 (COVID-19), has caused unprecedented morbidity and mortality worldwide. Scientific and clinical evidence testifies about long-term COVID-19 effects that can affect many organ systems. Cellular damage, overproduction of proinflammatory cytokines and […]

Some COVID-19 patients have brain complications, study suggests

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Authors: Mary Van Beusekom | News Writer | CIDRAP News  | Jun 26, 2020 Some COVID-19 patients, including those younger than 60 years old, appear to develop neurologic and neuropsychiatric complications such as stroke, brain inflammation, psychosis, and dementia-like symptoms, according to a study published yesterday in The Lancet Psychiatry. The early-stage study of 153 hospitalized patients with confirmed, probable, […]

Coronavirus and the Nervous System

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What is SARS-CoV-2 and COVID-19? What do we know about the effects of SARS-CoV-2 and COVID-19 on the nervous system? What are the immediate (acute) effects of SARS-CoV-2/COVID-19 on the brain? What is the typical recovery from COVID-19? What are possible long-term neurological complications of COVID-19? How do the long-term effects of SARS-CoV-2 infection/COVID-19 relate […]