Post-Spike Syndrome and Spikeopathy: Central Mechanisms in Long COVID Pathophysiology

November 25, 2025 | John Murphy | Leave a Comment

Post-Spike Syndrome and Spikeopathy: Central Mechanisms in Long COVID Pathophysiology

Author: John Murphy, President COVID 19 Long-haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), has emerged as a multifaceted syndrome affecting millions globally. While initial hypotheses…[...]

November 24, 2025 | John Murphy | Leave a Comment

🧠 Neurovascular Dysregulation and Microclot Persistence in COVID-19 Long-Haul Illnesses

Author: John Murphy, President, COVID-19 Long-haul Foundation 📑 Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), affects millions globally and presents with persistent symptoms including fatigue, cognitive dysfunction,…[...]

November 23, 2025 | John Murphy | Leave a Comment

Diagnostic Biomarkers and Imaging Modalities in Long COVID: Toward Precision Detection and Monitoring

Author: John Murphy, President, COVID-19 Long-haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), presents with a complex array of symptoms affecting multiple organ systems. Accurate diagnosis…[...]

November 22, 2025 | John Murphy | 2 Comments

Therapeutic Strategies and Clinical Trials in Long COVID: Anticoagulants, Fibrinolytics, Endothelial Support, Immunomodulators, and RECOVER Protocols

Author: John Murphy, President, COVID-19 Long-haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), is a chronic multisystem condition affecting millions globally. Despite its prevalence, therapeutic options…[...]

November 21, 2025 | John Murphy | Leave a Comment

Neuroinflammatory and Glutamatergic Dysregulation in Long COVID: Treating Brain Fog, Confusion, and Depression

John Murphy, – President, COVID-19 Long-haul Foundation Pathophysiology of Long COVID Neurocognitive Sequelae Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), is increasingly recognized as a chronic, multisystemic condition…[...]

November 20, 2025 | John Murphy | Leave a Comment

Endothelial Dysfunction and Spike Protein Persistence in Long COVID: Mechanisms, Vulnerabilities, and Clinical Evidence

Author: John Murphy, President, COVID-19 Long-haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), is characterized by persistent symptoms affecting multiple organ systems. Among its most compelling…[...]

November 19, 2025 | John Murphy | Leave a Comment

COVID Research Gaps and Future Directions: Standardization, Longitudinal Recovery, AI-Driven Biomarkers, and Policy Reform

Author: John Murphy, President, COVID-19 Long-haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), remains a poorly defined and under-researched condition affecting millions globally. Despite its prevalence,…[...]

November 18, 2025 | John Murphy | Leave a Comment

Potential Dysphagia Following COVID-19 Infection Due

Shuji Matsumoto • Rintaro Ohama • Takashi Hoei • Ryuji Tojo • Toshihiro Nakamura,, DOI: 10.7759/cureus.94248 Abstract The epiglottis separates the pharynx from the larynx by flipping upward to prevent swallowed material from entering the airway. Cervical vertebral osteophytes…[...]

November 17, 2025 | John Murphy | Leave a Comment

Exploring the Link Between COVID-19 and Liver Abscess Formation

Ramlakhan S. Verma • Shailendra Pal Singh • Gaurav Mishra • Vikas K. Patel • Vipin Gupta, DOI: 10.7759/cureus.94136 Abstract Background Liver abscess is a potential concern among liver health complications. With severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2)…[...]

November 16, 2025 | John Murphy | Leave a Comment

Dyslipidemia Associated With Type 2 Diabetes Mellitus as a Strong Predictor of ICU Admission

Abdurahman Alfaiz • Mohammad Shabbir • Mohammad D. Alotaibi • et. al., DOI: 10.7759/cureus.87193 Abstract Background: The global COVID-19 pandemic has raised questions about the complex interplay between chronic non-communicable diseases and the clinical trajectory of the…[...]