Pros and Cons of Adenovirus-Based SARS-CoV-2 Vaccines
Authors: Eric J. Kremer1,∗ Main Text Most of us might be surprised by the rudimentary scientific rationale prevalent in the field of vaccine research just 50 years ago. For over…[...]
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What are Adenovirus-Based Vaccines?
Authors: By Dr. Sanchari Sinha Dutta, Ph.D.Reviewed by Sophia Coveney, B.Sc. Adenoviruses are considered excellent vectors for delivering target antigens to mammalian hosts because of their capability to induce both innate and adaptive immune…[...]
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Adenovirus-vectored Vaccines for COVID-19 – How Do They Work?
Authors: Heather D. Marshall, PhD | Vito Iacoviello, MD Viruses are genetic material surrounded by a protein shell with the ability to infect cells, highjack cellular machinery, and make copies of themselves.…[...]
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Comorbidity and its Impact on Patients with COVID-19
Authors: Adekunle Sanyaolu 1, Chuku Okorie 2, Aleksandra Marinkovic 3, Risha Patidar 3, Kokab Younis 4, Priyank Desai 5, Zaheeda Hosein 6, Inderbir Padda 7, Jasmine Mangat 6, Mohsin Altaf 8 Abstract A novel human coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was identified in Wuhan, China, in…[...]
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Comparative study of hospitalized children with acute respiratory distress syndrome caused by SARS-CoV-2 and influenza virus
Authors: Xinghua Liu, Wei Li, Bo Zhang, Yan Guo, Zhao Hu, Cao Peng, Xiao Lei, Qunying Luo, Qiong hang, Wei Deng, Juanjuan Wang, Jianqiao Tang, Yunqiao Li & Jianying Chen BMC Infectious Diseases volume 21, Article number: 412 (2021) Abstract Background Since the outbreak of coronavirus disease 2019 in December…[...]
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COVID-19: an update and cardiac involvement
Authors: Nizar R. Alwaqfi & Khalid S. Ibrahim Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects host cells through angiotensin converting enzyme 2 receptors, leading to coronavirus disease (COVID-19)-related pneumonia, and…[...]
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Virology, transmission, and pathogenesis of SARS-CoV-2
Authors: Muge Cevik, clinical lecturer1 2, Krutika Kuppalli, assistant professor3, Jason Kindrachuk, assistant professor of virology4, Malik Peiris, professor of virology5 What you need to know SARS-CoV-2 is genetically similar to…[...]
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Severe covid-19 pneumonia: pathogenesis and clinical management
Authors: Amy H Attaway, assistant professor of medicine, associate director, COPD center1, Rachel G Scheraga, assistant professor of medicine1 2, Adarsh Bhimraj, head, section of neurological infections; staff, infectious diseases1, Michelle…[...]
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Neurologic Features in Severe SARS-CoV-2 Infection
Authors: Julie Helms, M.D., Ph.D., Stéphane Kremer, M.D., Ph.D., Hamid Merdji, M.D., Raphaël Clere-Jehl, M.D., Malika Schenck, M.D., Christine Kummerlen, M.D., Olivier Collange, M.D., Ph.D., Clotilde Boulay, M.D., Samira Fafi-Kremer,…[...]
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Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Children and Adolescents A Systematic Review
Authors: Riccardo Castagnoli, MD1,2; Martina Votto, MD1,2; Amelia Licari, MD1,2; et al Key Points Question What are the clinical features of pediatric patients with coronavirus disease 2019 (COVID-19)? Findings In this systematic review of 18 studies with 1065 participants, most pediatric…[...]
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