Antibody dependent enhancement: Unavoidable problems in vaccine development
Authors: Lele Xu, Zhiqian Ma, Yang Li, Zhaoxia Pang, and Shuqi Xiao* Adv Immunol. 2021; 151: 99–133.Published online 2021 Sep 4. doi: 10.1016/bs.ai.2021.08.003 PMCID: PMC8438590PMID: 34656289 Abstract In some cases, antibodies can enhance virus entry and replication in cells. This phenomenon is called antibody-dependent infection enhancement (ADE). ADE not only promotes the virus to be recognized by the target cell and enters the target […]