Prevention and Prophylaxis of SARS-CoV-2 Infection


Authors: NIH The COVID-19 Treatment Guidelines Panel (the Panel) recommends that health care providers follow recommendations from the Advisory Committee on Immunization Practices when using SARS-CoV-2 vaccines (AI).The Panel recommends against the use of any drugs for SARS-CoV-2 pre-exposure prophylaxis (PrEP), except in a clinical trial (AIII).The Panel recommends against the use of hydroxychloroquine for […]

How COVID-19 Spreads


Authors: CDC COVID-19 spreads when an infected person breathes out droplets and very small particles that contain the virus. These droplets and particles can be breathed in by other people or land on their eyes, noses, or mouth. In some circumstances, they may contaminate surfaces they touch. People who are closer than 6 feet from the infected person are most likely to […]

Respiratory follow-up of patients with COVID-19 pneumonia


Authors: http://orcid.org/0000-0003-1316-4891Peter M George1,2, http://orcid.org/0000-0003-3067-7349Shaney L Barratt3,4, Robin Condliffe5, Sujal R Desai6, Anand Devaraj6, Ian Forrest7, Michael A Gibbons8, Nicholas Hart9, http://orcid.org/0000-0002-7929-2119R Gisli Jenkins10, Danny F McAuley11, Brijesh V Patel12, Erica Thwaite13, Lisa G Spencer13 The COVID-19 pandemic has led to an unprecedented surge in hospitalised patients with viral pneumonia. The most severely affected patients are older men, individuals of black and Asian minority ethnicity and those […]

Preliminary Findings of mRNA Covid-19 Vaccine Safety in Pregnant Persons


Authors: Tom T. Shimabukuro, M.D., Shin Y. Kim, M.P.H., Tanya R. Myers, Ph.D., Pedro L. Moro, M.D., Titilope Oduyebo, M.D., Lakshmi Panagiotakopoulos, M.D., Paige L. Marquez, M.S.P.H., Christine K. Olson, M.D., Ruiling Liu, Ph.D., Karen T. Chang, Ph.D., Sascha R. Ellington, Ph.D., Veronica K. Burkel, M.P.H., et al., for the CDC v-safe COVID-19 Pregnancy Registry Team* Many pregnant persons in the United States are receiving messenger RNA (mRNA) […]

Extrapulmonary manifestations of COVID-19


Authors: Aakriti Gupta, Mahesh V. Madhavan, […]Donald W. Landry Although COVID-19 is most well known for causing substantial respiratory pathology, it can also result in several extrapulmonary manifestations. These conditions include thrombotic complications, myocardial dysfunction and arrhythmia, acute coronary syndromes, acute kidney injury, gastrointestinal symptoms, hepatocellular injury, hyperglycemia and ketosis, neurologic illnesses, ocular symptoms, and dermatologic complications. […]

Filtration Efficiency, Effectiveness, and Availability of N95 Face Masks for COVID-19 Prevention


Authors: Caitlin M. Dugdale, MD1,2; Rochelle P. Walensky, MD, MPH In March 2020, the soaring number of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections resulted in an unprecedented shortage of personal protective equipment (PPE) for clinicians and essential health care workers.1 The shortage was most profound among N95 masks. N95 respirators, named for their ability to filter 95% or more […]

Coronavirus Recovery: Breathing Exercises


Authors: Peiting Lien, DPT, PT The coronavirus that causes COVID-19 attacks the lungs and respiratory system, sometimes resulting in significant damage. COVID-19 often leads to pneumonia and even acute respiratory distress syndrome (ARDS), a severe lung injury. Recovering lung function is possible but can require therapy and exercises for months after the infection is treated. “Working toward recovery […]

Viral dynamics in mild and severe cases of COVID-19


Authors: Lancet Correspondence Coronavirus disease 2019 (COVID-19) is a new pandemic disease. We previously reported that the viral load of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) peaks within the first week of disease onset.1, 2 Findings from Feb, 2020, indicated that the clinical spectrum of this disease can be very heterogeneous.3 Here, we report the viral RNA […]

Long covid: How to define it and how to manage it


Authors: Nikki Nabavi, editorial scholar “Profound fatigue” was a common symptom in most people with long covid, she said, but added that a wide range of other symptoms included cough, breathlessness, muscle and body aches, and chest heaviness or pressure, but also skin rashes, palpitations, fever, headache, diarrhoea, and pins and needles. “A very common […]