Cytokeratin 18 cell death assays as biomarkers for quantification of apoptosis and necrosis in COVID-19: a prospective, observational study

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Authors: Brandon Michael Henry1, http://orcid.org/0000-0002-1211-8247Isaac Cheruiyot2, Stefanie W Benoit3,4, Fabian Sanchis-Gomar5,6, http://orcid.org/0000-0001-9523-9054Giuseppe Lippi7, Justin Benoit8 Correspondence to Dr Brandon Michael Henry, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, USA; Abstract Background The mechanism by which SARS-CoV-2 triggers cell damage and necrosis are yet to be fully elucidated. We sought to quantify epithelial cell death in patients with COVID-19, with an estimation of […]

Coronavirus (Covid-19)

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A collection of articles and other resources on the Coronavirus (Covid-19) outbreak, including clinical reports, management guidelines, and commentary. CORONAVIRUS (COVID-19)     VACCINE RESOURCES     VACCINE FAQ https://www.nejm.org/coronavirus All Journal content related to the Covid-19 pandemic is freely available. ORIGINAL ARTICLEConvalescent Plasma for High-Risk Covid-19F.K. Korley and OthersPatients who were seen in emergency departments within 7 days after the onset of Covid-19 symptoms […]

Prevalence of Depression, Anxiety, and Stress during COVID-19 Pandemic

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Authors: Ram Lakhan1 Amit Agrawal2 Manoj Sharma3 Introduction The outbreak of the third coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV2), also named coronavirus disease 2019 (COVID-19), has occurred more rapidly than people could have ever imagined from the experience of the past two SARS-CoV and Middle East respiratory syndrome coronavirus.1,2 To control the spread […]

Prevalence of Depression, Anxiety, and Stress during COVID-19 Pandemic

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Authors: Ram Lakhan 1, Amit Agrawal 2, Manoj Sharma 3 Abstract The coronavirus disease 2019 (COVID-19) crisis has greatly affected human lives across the world. Uncertainty and quarantine have been affecting people’s mental health. Estimations of mental health problems are needed immediately for the better planning and management of these concerns at a global level. A rapid scoping review was […]

Covid-19 Vaccine Analysis: The most common adverse events reported so far

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Authors: DATED: AUGUST 6, 2021 BY SHARYL ATTKISSON  As of July 19, 2021 there were 419,513 adverse event reports associated with Covid-19 vaccination in the U.S., with a total of 1,814,326 symptoms reported. That’s according to the federal Vaccine Adverse Event Reporting System (VAERS) database. Report an adverse event after vaccination online here. Each symptom reported does […]

More than 50 Long-Term Effects of COVID-19: A Systematic Review and Meta-Analysis

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Authors: López-León S, Wegman-Ostrosky T, Perelman C, Sepulveda R, Rebolledo PA, Cuapio A, Villapol S Preprint from SSRN, 20 Jan 2021 Abstract  Background: COVID-19, caused by SARS-CoV-2, can involve sequelae that last weeks to months after initial recovery. The objective of this systematic review and meta-analysis is to identify studies assessing the long-term effects of COVID-19 and estimate the prevalence of each symptom, […]

Cognitive Impairment After COVID-19—A Review on Objective Test Data

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Authors: Rania Daroische1*, Mathilde S. Hemminghyth1,2, Thomas H. Eilertsen1, Monica H. Breitve1,2,3 and Luiza J. Chwiszczuk2,3 Objective: The aim was to conduct a review on the literature on objective cognitive impairment in patients after COVID-19. Methods: We performed a literature review and searched Ovid Medline in February 2021 based on a PECO scheme. Results: Twelve articles met all inclusion criteria. Total patient sample […]

Prevalence of anosmia and ageusia symptoms among long-term effects of COVID-19.

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Authors: Moraschini V1, Reis D1, Sacco R2, Calasans-Maia MD3 COVID‐19 is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) that currently presents the greatest, most challenging health concern worldwide. Since the first reports of the disease in December 2019, clinicians and scientists have endeavored to understand the main symptoms, risk factors, and prognosis of […]

Characteristics of SARS-CoV-2 and COVID-19

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Authors: Ben Hu, Hua Guo, Peng Zhou & Zheng-Li Shi  Nature Reviews Microbiology volume 19, pages141–154 (2021) Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible and pathogenic coronavirus that emerged in late 2019 and has caused a pandemic of acute respiratory disease, named ‘coronavirus disease 2019’ (COVID-19), which threatens human health and public safety. In this Review, we […]

COVID-19 related concerns of people with long-term respiratory conditions: a qualitative study

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Authors: Keir E. J. Philip,  Bradley Lonergan, Andrew Cumella, Joe Farrington-Douglas, Michael Laffan & Nicholas S. Hopkinson BMC Pulmonary Medicine volume 20, Article number: 319 (2020)  Abstract Background The COVID-19 pandemic is having profound psychological impacts on populations globally, with increasing levels of stress, anxiety, and depression being reported, especially in people with pre-existing medical conditions who appear to be particularly vulnerable. There are limited data […]