Platelet Indices as Novel Surrogate Markers for the Prognosis of COVID-19 Infection: An Observational Study

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Vivek Lahane • Sourya Acharya • Samarth Shukla • et. al. June 12, 2024 DOI: 10.7759/cureus.62243  Abstract Background  The new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes severe acute respiratory illness accountable for causing the coronavirus disease 2019 (COVID-19) illness. Thrombotic issues, acute respiratory distress syndrome (ARDS), and cytokine storm are significant contributors to morbidity and mortality in patients with COVID-19. Elevated D-dimer […]

Impact of Covid-19 on Psychosocial Well-Being of School-Going Children: A Cross-Sectional Study

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Deepti Damayanty Pradhan • Pravati Jena • Sreesom Misra • et. al.  June 17, 202 DOI: 10.7759/cureus.62561  Abstract Introduction: The mandated closure of schools due to Covid-19 is likely to have a negative impact on school-going children. This study aimed to assess the psychosocial well-being of school children during the pandemic in eastern India. Methods: This cross-sectional study was conducted in the […]

The Real Covid Failure

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Its superfast spread told us early the virus was unstoppable and likely lab-modified. By Holman W. Jenkins, Jr., June 18, 2024 Wall Street Journal You didn’t think any question related to Covid would be settled in the recent congressional grilling of Anthony Fauci and you were right. That’s why the episode came and went from your news feed […]

New Report Reviews Evidence on Long COVID Diagnosis, Risk, Symptoms, and Functional Impact for Patients

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News Release | June, 2024 National Academies of Science & Engineering WASHINGTON — A new report from the National Academies of Sciences, Engineering, and Medicine presents conclusions about Long COVID diagnosis, symptoms, and impact on daily function — including that Long COVID can cause more than 200 symptoms, and that a positive COVID-19 test is not necessary to make […]

Pathophysiological, immunological, and inflammatory features of long COVID

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Karen Bohmwald1,2†Benjamín Diethelm-Varela, et. al., Front. Immunol., 27 February 2024,Sec. Viral ImmunologyVolume 15 – 2024 | https://doi.org/10.3389/fimmu.2024.1341600 The COVID-19 pandemic continues to cause severe global disruption, resulting in significant excess mortality, overwhelming healthcare systems, and imposing substantial social and economic burdens on nations. While most of the attention and therapeutic efforts have concentrated on the acute […]

Complement system causes cell damage in long Covid

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January, 2024, Source: University of Zurich Science Daily Summary: Long Covid patients suffer from chronic symptoms such as fatigue or shortness of breath. As researchers have discovered, this is to some extent due to a part of our immune system called the complement system. The study identified a pattern in the blood proteins that will […]

Improvement of immune dysregulation in individuals with long COVID at 24-months following SARS-CoV-2 infection

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Chansavath Phetsouphanh, Brendan Jacka, et. al., Nature Communications volume 15, Article number: 3315 (2024) Abstract This study investigates the humoral and cellular immune responses and health-related quality of life measures in individuals with mild to moderate long COVID (LC) compared to age and gender matched recovered COVID-19 controls (MC) over 24 months. LC participants show elevated nucleocapsid IgG levels at 3 months, […]

The knowns and unknowns of long COVID-19: from mechanisms to therapeutical approaches

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Roxana Gheorghita1,2Iuliana Soldanescu3Andrei Lobiuc, et. al. , Frontiers in Medicine The coronavirus disease 2019 (COVID-19) pandemic caused by SARS-CoV-2 has been defined as the greatest global health and socioeconomic crisis of modern times. While most people recover after being infected with the virus, a significant proportion of them continue to experience health issues weeks, months […]

Systems Modeling Reveals Shared Metabolic Dysregulation and Novel Therapeutic Treatments in ME/CFS and Long COVID

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Gong-Hua Li, Feifei Han, Qing-Peng Kong, Wenzhong Xiao, doi: https://doi.org/10.1101/2024.06.17.599450 Abstract Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Long COVID are complex, multisystemic conditions that pose ongoing challenges to healthcare professionals. Emerging research suggests that ME/CFS and Long COVID exhibit overlapping metabolic symptoms, indicating possible shared metabolic dysfunctions. This study aims to systematically explore these shared metabolic disturbances and their potential treatments. Utilizing our […]

Scientific expert declares there is ‘zero’ evidence for natural COVID-19 origin

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Josh Christenson, 2024, New York Post A panel of scientists fiercely debated Tuesday whether COVID-19 stemmed from a laboratory accident or naturally spread from animals to humans, with one expert declaring there was “zero” evidence for a natural origin of the pandemic that killed millions around the world. Rutgers University molecular biologist Dr. Richard Ebright said in his […]