Associations between body-mass index and COVID-19 severity in 6·9 million people in England: a prospective, community-based, cohort study


Authors: Min Gao, MSc *, Carmen Piernas, PhD  , Nerys M Astbury, PhD, Prof Julia Hippisley-Cox, FRCPProf Stephen O’Rahilly, FRS, Prof Paul Aveyard, FRCGP † Summary Background Obesity is a major risk factor for adverse outcomes after infection with SARS-CoV-2. We aimed to examine this association, including interactions with demographic and behavioural characteristics, type 2 diabetes, and other […]

Histopathological observations in COVID-19: a systematic review


Authors: Vishwajit Deshmukh1, Rohini Motwani, Ashutosh Kumar3, Chiman Kumari4, Khursheed Raza5 Correspondence to Dr Rohini Motwani, Department of Anatomy, ESIC Medical College and Hospital, Sanathnagar, Hyderabad, Telangana, India; rohinimotwani@gmail.com Abstract Background Coronavirus disease-2019 (COVID-19) has caused a great global threat to public health. The World Health Organization (WHO) has declared COVID-19 disease as a pandemic, affecting the human respiratory and other […]

Age-dependent appearance of SARS-CoV-2 entry sites in mouse chemosensory systems reflects COVID-19 anosmia-ageusia symptoms


Authors: Julien Brechbühl,Ana Catarina Lopes,Dean Wood,Sofiane Bouteiller,Aurélie de Vallière,Chantal Verdumo, and Marie-Christine Broillet Abstract COVID-19 pandemic has given rise to a collective scientific effort to study its viral causing agent SARS-CoV-2. Research is focusing in particular on its infection mechanisms and on the associated-disease symptoms. Interestingly, this environmental pathogen directly affects the human chemosensory systems leading to […]

Stress-Related Growth in Adolescents Returning to School After COVID-19 School Closure


Authors: Lea Waters,1,*Kelly-Ann Allen,1,2 and Gökmen Arslan3,4 Abstract The move to remote learning during COVID-19 has impacted billions of students. While research shows that school closure, and the pandemic more generally, has led to student distress, the possibility that these disruptions can also prompt growth in is a worthwhile question to investigate. The current study examined stress-related […]

US case series study in children study looking at association of myocarditis with the Pfizer-BioNTech COVID-19 vaccine


Authors: byUK Science Media Centre|Published onAugust 10, 2021: Prof Peter Openshaw In this case series, 15 cases of myocarditis are described from a single paediatric referral centre in May, June and July 2021.  Each had been given the Pfizer mRNA vaccine between 1 and 6 days prior to diagnosis; children were aged 12-18 years.  In […]

Psychological Impact of COVID-19 on Children and Adolescents: A Systematic Review


Authors: Nishtha Chawla,1Ashlyn Tom,1Mahadev Singh Sen,1 and Rajesh Sagar1 Abstract Background and aims: The outbreak of COVID-19 led to a significant psychological impact on individuals, particularly those belonging to vulnerable groups. This study aimed to synthesize literature on the psychological impact of COVID-19 among children and adolescents. Methods: Electronic search engines were used to identify studies till […]

Evaluation of the safety of mRNA-Moderna in adolescents


Authors: Killian Meara The vaccine demonstrated an acceptable safety profile in the adolescent population. A recent study conducted by investigators from the pharmaceutical and biotechnology company, Moderna, has found that their COVID-19 vaccine, mRNA-1273, was both safe and efficacious in preventing COVID-19 in adolescents. Results from the study were published in The New England Journal of […]

Individual differences in adolescent mental health during COVID-19: The importance of peer relationship quality


By DocWire News Featured Reading -August 11, 2021 Neuron. 2021 Aug 9:S0896-6273(21)00571-7. doi: 10.1016/j.neuron.2021.07.027. Online ahead of print. ABSTRACT Lockdowns and school closures deprive adolescents of typical social interactions. In this NeuroView, we explore how the quality of existing peer relationships might moderate-both positively and negatively-the impact of these restrictions on adolescent mental health, and we highlight […]

Stress-Related Growth in Adolescents Returning to School After COVID-19 School Closure


Authors: Lea Waters1*, Kelly-Ann Allen1,2 and Gökmen Arslan3,4 The move to remote learning during COVID-19 has impacted billions of students. While research shows that school closure, and the pandemic more generally, has led to student distress, the possibility that these disruptions can also prompt growth in is a worthwhile question to investigate. The current study examined stress-related growth […]

Lack of antibodies against seasonal coronavirus OC43 nucleocapsid protein identifies patients at risk of critical COVID-19


Authors: MartinDugasa1TanjaGrote-Westrickb1UtaMerledMichaelaFontenaylmAndreas E.KremerhFrankHansesijRichardVollenbergcEvaLorentzenbShilpaTiwari-BecklerdJérômeDucheminlSyrineEllouzelMarcelVetterhJuliaFürsthPhilippSchusterkTobiasBrixaClaudia M.DenkingerfgCarstenMüller-TidoweHartmutSchmidtc…JoachimKühnb1 Highlights Does prior infection with seasonal human coronavirus OC43 protect against critical COVID-19?• Findings: In an international multi-center study inpatients without anti-HCoV OC43 NP antibodies had an increased risk of critical disease.• Meaning: Prior infections with seasonal HCoV OC43 have a protective effect against critical COVID-19. Abstract Background The vast majority of COVID-19 patients experience […]