Posted on | Posted on John Murphy | Leave a Comment on ChAdOx1 interacts with CAR and PF4 with implications for thrombosis with thrombocytopenia syndrome

ChAdOx1 interacts with CAR and PF4 with implications for thrombosis with thrombocytopenia syndrome

Authors: ALEXANDER T. BAKERHTTPS://ORCID.ORG/0000-0001-8232-0531RYAN J. BOYDHTTPS://ORCID.ORG/0000-0002-6704-8696DAIPAYAN SARKARHTTPS://ORCID.ORG/0000-0002-4167-2108ALICIA TEIJEIRA-CRESPOCHUN KIT CHANEMILY BATESHTTPS://ORCID.ORG/0000-0003-1378-6981KASIM WARAICHHTTPS://ORCID.ORG/0000-0002-2927-7383JOHN VANTHTTPS://ORCID.ORG/0000-0003-0627-4603ERIC WILSONHTTPS://ORCID.ORG/0000-0002-4104-1445[...]MITESH J. BORADHTTPS://ORCID.ORG/0000-0003-2700-2658 +16 authors Authors Info & Affiliations Abstract Vaccines derived from chimpanzee adenovirus Y25 (ChAdOx1), human adenovirus type 26 (HAdV-D26), and human adenovirus type 5 (HAdV-C5) are…[...]

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Posted on | Posted on John Murphy | Leave a Comment on Abstract 10712: Mrna COVID Vaccines Dramatically Increase Endothelial Inflammatory Markers and ACS Risk as Measured by the PULS Cardiac Test: a Warning

Abstract 10712: Mrna COVID Vaccines Dramatically Increase Endothelial Inflammatory Markers and ACS Risk as Measured by the PULS Cardiac Test: a Warning

Authors: Steven R Gundry Originally published 8 Nov 2021Circulation. 2021;144:A10712 Abstract Our group has been using the PLUS Cardiac Test (GD Biosciences, Inc, Irvine, CA) a clinically validated measurement of…[...]

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Posted on | Posted on John Murphy | Leave a Comment on Antigen Presentation of mRNA-Based and Virus-Vectored SARS-CoV-2 Vaccines

Antigen Presentation of mRNA-Based and Virus-Vectored SARS-CoV-2 Vaccines

Authors: Ger T. Rijkers,1,2,* Nynke Weterings,1 Andres Obregon-Henao,3 Michaëla Lepolder,1 Taru S. Dutt,3 Frans J. van Overveld,1 and Marcela Henao-Tamayo3 Abstract Infection with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) causes Coronavirus Disease 2019 (COVID-19), which has…[...]

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Posted on | Posted on John Murphy | Leave a Comment on SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE 2

SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE 2

Authors: Yuyang Lei,1,2,*Jiao Zhang,1,2,5,*Cara R. Schiavon,8,9Ming He,5Lili Chen,2Hui Shen,5,10Yichi Zhang,5Qian Yin,2Yoshitake Cho,5Leonardo Andrade,8Gerald S. Shadel,9Mark Hepokoski,6Ting Lei,3Hongliang Wang,4Jin Zhang,7Jason X.-J. Yuan,6Atul Malhotra,6Uri Manor,8,†Shengpeng Wang,2,†Zu-Yi Yuan,1,† and John Y-J. Shyy5,† SARS-CoV-2 (severe acute…[...]

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Posted on | Posted on John Murphy | Leave a Comment on Impact and effectiveness of mRNA BNT162b2 vaccine against SARS-CoV-2 infections and COVID-19 cases, hospitalizations, and deaths following a nationwide vaccination campaign in Israel: an observational study using national surveillance data

Impact and effectiveness of mRNA BNT162b2 vaccine against SARS-CoV-2 infections and COVID-19 cases, hospitalizations, and deaths following a nationwide vaccination campaign in Israel: an observational study using national surveillance data

Eric J HaasFrederick J AnguloJohn M McLaughlinEmilia AnisShepherd R SingerFarid KhanNati BrooksMeir SmajaGabriel MircusKaijie PanJo SouthernDavid L SwerdlowLuis JodarYeheskel LevySharon Alroy-PreisAuthors: During the analysis period (Jan 24 to April 3,…[...]

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Posted on | Posted on John Murphy | Leave a Comment on Effectiveness of mRNA BNT162b2 COVID-19 vaccine up to 6 months in a large integrated health system in the USA: a retrospective cohort study

Effectiveness of mRNA BNT162b2 COVID-19 vaccine up to 6 months in a large integrated health system in the USA: a retrospective cohort study

Authors: Sara YTartofPhDaeJeff MSlezakMSaHeidiFischerPhDaVennisHongMPHaBradley KAckersonMDbOmesh NRanasingheMPHaTimothy BFranklandMAcOluwaseye AOgunMDaJoann MZamparoMPHdSharonGrayMSdSrinivas RValluriPhDdKaijePanMSdFrederick JAnguloPhDdLuisJodarPhDdJohn MMcLaughlinPhDd Between Dec 14, 2020, and Aug 8, 2021, of 4 920 549 individuals assessed for eligibility, we included 3 436 957 (median…[...]

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