The beneficial and pathogenic roles of complement in COVID-19
Alfred H.J. Kim, MD, PhD, Xiaobo Wu, MD and John P. Atkinson, MD Cleveland Clinic Journal of Medicine October 2020, DOI: https://doi.org/10.3949/ccjm.87a.ccc065 ABSTRACT We briefly summarize the complement system and its functions in immunity and disease. We present data supporting the requirement of complement to resolve COVID-19, and discuss how complement overactivation later in severe disease could drive multiorgan damage characteristic of fatal COVID-19. INTRODUCTION The […]